HB sperm demonstrate enhanced developmental parameters which have been associated with successful fertilization and embryogenesis. Citing articles via Web of Science Close mobile search navigation Article navigation. Throughout the clinical trial, there were no demonstrated negative effects associated with measures of preimplantation embryogenesis and the use of hyaluronan in sperm selection for ICSI. The in vitro binding of sperm to hyaluronan is a selective process. Visual assessment alone can allow the inadvertent selection of sperm with compromised developmental, nuclear and cytoplasmic competence.
They bred in the upper spawning ground
Survival of the fittest sperm: How new technology may help infertile couples
Use of the I-HB score as the determination for the use of HB sperm in ICSI would provide the best balance between providing unnecessary treatment versus denying patients treatment that may improve their clinical outcome. The injection procedure itself can also be influenced by oocyte characteristics. Median and interquartile ranges are reported. Sign In or Create an Account. Correction factors have been developed and should be used when screening for Down syndrome in singleton pregnancies after ICSI,  but in twin pregnancies such correction factors have not been fully elucidated.